Bonner Natural Health

Suppository Manufacturing Protocol

Two strengths of a single blend. Three hundred units of 2 mL per batch, moulded and sealed in individual shells, boxed in thirties. Each part is complete on its own.

Author Barry Bonner Company Bonner Biotech LLC Contact +1 415 515 1665 Email barry@bonnerbiotech.com

BON-SuppMfg-060926-v04

Part One Foundation 130 mg of cannabinoid per suppository. The introductory strength. Also the reset protocol at one month or three months. Part Two Advanced Care 400 mg per suppository. The same blend at roughly three times the strength, for sustained daily support.

Charges, Both Products

Weigh out for 300 units
Ingredient	Foundation	Advanced Care	Note
Apricot kernel oil	170 mL	170 mL
Distillate BK-26-045	20.93 g	64.39 g
CBD isolate	5.13 g	15.79 g
CBG isolate	7.90 g	24.30 g
CBN isolate	5.13 g	15.79 g
CBDa isolate	3.16 g	9.72 g
CBGa isolate	3.82 g	11.74 g	weighed at 72%
CBC liquid	1.42 g	4.37 g
Cocoa butter	412.5 g	314.0 g
Total input	615 g	615 g
Filled, 300 units at 1.96 g	588 g	588 g

Per finished suppository
	Foundation	Advanced Care	Limit
Cannabinoid delivered	130 mg	400 mg
Total THC, worst case	0.019 mg	0.057 mg	0.400 mg

THC limit is per sealed shell, from 12 November 2026.

Part One of two

Foundation

Batch 300 units, 2 mL Unit weight 1.96 g plus or minus 0.04 Delivered 130 mg per suppository THC per suppository 0.019 mg

1.1 Stages

Step	What goes in	Temperature	Check
Prep	Apricot kernel oil 170 mL, distillate, isolates, CBC	75 to 77 °C 168 to 170 °F	Completely clear. No crystals, no grit.
A	Cocoa butter 412.5 g	36 to 38 °C 97 to 100 °F	Bath at 45 °C. Lift out at 38 °C.
B	The concentrate	36 to 38 °C 97 to 100 °F	Both streams within two degrees.
Fill	Nothing. Pour the shells.	34 to 36 °C 93 to 97 °F	Stir the jug between rows.
Cap	Concentrate max 85 °C / 185 °F. Cocoa butter max 40 °C / 104 °F.		Above 40 °C the units will not set hard.

1.2 Equipment

Item	Specification	Note
Beaker, primary	1,000 mL borosilicate	Batch about 640 mL molten.
Beaker, concentrate	400 mL borosilicate	Concentrate about 200 mL.
Water bath	Set 45 °C	Cocoa butter only.
Hotplate stirrer	Controlled	Concentrate only, runs at 77 °C.
Probe thermometer	Calibrated, fast reading	Tip in the liquid, not on the glass.
Digital scale	0.01 g, capacity 3 kg
Measuring cylinder	250 mL	Apricot kernel oil.
Pouring jug	Warmed to 36 °C
Mould shells	2 mL sealable, in strips	300 plus 10 spare. Cool to 15 to 20 °C.
Heat sealer	For the shell fin
PPE	Gloves, glasses, coat, closed shoes

1.3 Concentrate

PrepDissolve the actives75 to 77 °C / 168 to 170 °F

170 mL apricot kernel oil into the 400 mL beaker.
Warm to 75 to 77 °C, 168 to 170 °F.
Distillate 20.93 g, lot BK-26-045. Stir until dispersed.
Isolates one at a time, each clear before the next. CBD 5.13, CBG 7.90, CBN 5.13, CBDa 3.16, CBGa 3.82 g.
CBC liquid 1.42 g. Stir in.
Stir to completely clear. Test a drop on cold glass.
Under fifteen minutes above 70 °C.
Off the heat. Cool to 36 to 38 °C, 97 to 100 °F. If it clouds, reheat to 77 °C and record.

1.4 Batch Sheet

Foundation, 300 units at 2 mL
Step	Ingredient	Per 300	Delivered per unit
Prep	Apricot kernel oil	170 mL
Prep	Distillate BK-26-045	20.93 g	49.1 mg
Prep	CBD isolate	5.13 g	16.3 mg
Prep	CBG isolate	7.90 g	25.1 mg
Prep	CBN isolate	5.13 g	16.3 mg
Prep	CBDa isolate	3.16 g	10.0 mg
Prep	CBGa isolate, 72%	3.82 g	8.8 mg
Prep	CBC liquid	1.42 g	4.5 mg
A	Cocoa butter	412.5 g
Total input		615 g	130 mg
Filled		588 g	1.96 g

Residue expected under 45 g.

1.5 Process

Stage AMelt the cocoa butter36 to 38 °C / 97 to 100 °F

412.5 g cocoa butter into the 1 L beaker. Pastilles or shavings, not a block.
Bath at 45 °C, 113 °F. Stir every few minutes.
Lift the beaker out at 37 to 38 °C, 99 to 100 °F, last solid gone. Expect 20 to 25 minutes.
Start this while the concentrate is cooling so the two arrive together.

Stage BCombine36 to 38 °C / 97 to 100 °F

Both streams within two degrees, 36 to 38 °C.
Pour the concentrate in slowly, stirring throughout.
Rinse the concentrate beaker with warm blend and return it.
Stir three to five minutes to even colour, no streaking.

FillPour the shells34 to 36 °C / 93 to 97 °F

All 300 shells racked, open, cooled to 15 to 20 °C before starting.
Into the warmed jug. Fill each cavity slightly proud of the rim.
Stir the jug between every row.
Weigh one unit every twentieth cavity. 1.96 g, tolerance 0.04 g.
Below 33 °C, 91 °F, return to the bath and bring back to 35 °C. Once only.
Set at room temperature 20 minutes, then 15 °C for one hour.
Seal the fin only when fully firm.
Mark each shell with product and batch number. Sleeve in thirties, box.

No freezer.

1.6 Release Checks

Check	Target	Method
Appearance	Smooth, no cavity at the tip	Hollow tip means the pour was too cool.
Surface	No white film at 24 hours	Bloom means the cocoa butter was overheated. Hold the batch.
Firmness	Hard at 20 °C	Press one unit through the shell. Any give is a reject.
Unit weight	1.96 g plus or minus 0.04 g	Ten units across the batch, tared against an empty shell.
Melt	Collapses within 15 minutes at 37 °C	One unit in a water bath at body temperature.
Colour	Even through the length	Cut one lengthways. Streaking means the jug was not stirred.
Seal	Intact on every shell	Squeeze test on ten.

Any result outside target holds the batch.

1.7 Batch Record

Foundation
Batch number		BNH-FDN-____
Date and operator
Distillate lot
CBD, CBG, CBN isolate lots
CBDa, CBGa isolate lots
CBC liquid lot
Cocoa butter and apricot oil lots
Concentrate clear		yes or no
Concentrate reheated		yes or no
Cocoa butter melt time		minutes
Peak temperature, cocoa butter		°C, max 40
Both streams at Stage B		°C
First pour		°C
Last pour		°C, above 33
Reheat during pour		yes or no
Units filled		expect 300
Mean unit weight		g
Residue in beaker		g, under 45
Bloom check at 24 hours		pass or hold
Deviations
Released by and date

Part Two of two

Advanced Care

Batch 300 units, 2 mL Unit weight 1.96 g plus or minus 0.04 Delivered 400 mg per suppository THC per suppository 0.057 mg

2.1 Stages

Step	What goes in	Temperature	Check
Prep	Apricot kernel oil 170 mL, distillate, isolates, CBC	75 to 77 °C 168 to 170 °F	Heavy load. Completely clear, no grit.
A	Cocoa butter 314 g	36 to 38 °C 97 to 100 °F	Bath at 45 °C. Lift out at 38 °C.
B	The concentrate	36 to 38 °C 97 to 100 °F	Both streams within two degrees.
Fill	Nothing. Pour the shells.	34 to 36 °C 93 to 97 °F	Settles faster than Foundation. Stir every row.
Cap	Concentrate max 85 °C / 185 °F. Cocoa butter max 40 °C / 104 °F.		Above 40 °C the units will not set hard.

2.2 Equipment

Item	Specification	Note
Beaker, primary	1,000 mL borosilicate	Batch about 640 mL molten.
Beaker, concentrate	400 mL borosilicate	Concentrate about 300 mL.
Water bath	Set 45 °C	Cocoa butter only.
Hotplate stirrer	Controlled	Concentrate only, runs at 77 °C.
Probe thermometer	Calibrated, fast reading	Tip in the liquid, not on the glass.
Digital scale	0.01 g, capacity 3 kg
Measuring cylinder	250 mL	Apricot kernel oil.
Pouring jug	Warmed to 36 °C
Mould shells	2 mL sealable, in strips	300 plus 10 spare. Cool to 15 to 20 °C.
Heat sealer	For the shell fin
PPE	Gloves, glasses, coat, closed shoes

2.3 Concentrate

PrepDissolve the actives75 to 77 °C / 168 to 170 °F

170 mL apricot kernel oil into the 400 mL beaker.
Warm to 75 to 77 °C, 168 to 170 °F.
Distillate 64.39 g, lot BK-26-045. Stir until dispersed.
Isolates one at a time, each clear before the next. CBD 15.79, CBG 24.30, CBN 15.79, CBDa 9.72, CBGa 11.74 g.
CBC liquid 4.37 g. Stir in.
Stir to completely clear. Takes longer than Foundation. Test a drop on cold glass.
Under twenty minutes above 70 °C.
Off the heat. Cool to 36 to 38 °C, 97 to 100 °F. If it clouds or thickens, reheat to 77 °C and record.
Do not combine a concentrate that is not clear.

2.4 Batch Sheet

Advanced Care, 300 units at 2 mL
Step	Ingredient	Per 300	Delivered per unit
Prep	Apricot kernel oil	170 mL
Prep	Distillate BK-26-045	64.39 g	151.1 mg
Prep	CBD isolate	15.79 g	50.1 mg
Prep	CBG isolate	24.30 g	77.1 mg
Prep	CBN isolate	15.79 g	50.2 mg
Prep	CBDa isolate	9.72 g	30.7 mg
Prep	CBGa isolate, 72%	11.74 g	26.9 mg
Prep	CBC liquid	4.37 g	13.9 mg
A	Cocoa butter	314.0 g
Total input		615 g	400 mg
Filled		588 g	1.96 g

Residue expected under 45 g.

2.5 Process

Stage AMelt the cocoa butter36 to 38 °C / 97 to 100 °F

314.0 g cocoa butter into the 1 L beaker. Pastilles or shavings, not a block.
Bath at 45 °C, 113 °F. Stir every few minutes.
Lift the beaker out at 37 to 38 °C, 99 to 100 °F, last solid gone. Expect 15 to 20 minutes.
Start this while the concentrate is cooling so the two arrive together.

Stage BCombine36 to 38 °C / 97 to 100 °F

Both streams within two degrees, 36 to 38 °C, concentrate still clear.
Pour the concentrate in slowly, stirring throughout.
Rinse the concentrate beaker with warm blend and return it.
Stir three to five minutes to even colour, no streaking.

FillPour the shells34 to 36 °C / 93 to 97 °F

All 300 shells racked, open, cooled to 15 to 20 °C before starting.
Into the warmed jug. Fill each cavity slightly proud of the rim.
Stir the jug between every row. Four times the actives of Foundation, settles faster.
Weigh one unit every twentieth cavity. 1.96 g, tolerance 0.04 g.
Below 33 °C, 91 °F, return to the bath and bring back to 35 °C. Once only.
Set at room temperature 20 minutes, then 15 °C for one hour.
Seal the fin only when fully firm.
Mark each shell with product and batch number. Sleeve in thirties, box.

No freezer.

2.6 Release Checks

Check	Target	Method
Appearance	Smooth, no cavity at the tip	Hollow tip means the pour was too cool.
Surface	No white film at 24 hours	Bloom means the cocoa butter was overheated. Hold the batch.
Grit	None	Cut and press a unit. Grain means the concentrate was not clear at 2.3.
Firmness	Hard at 20 °C	Press one unit through the shell. Any give is a reject.
Unit weight	1.96 g plus or minus 0.04 g	Ten units across the batch, tared against an empty shell.
Melt	Collapses within 15 minutes at 37 °C	One unit in a water bath at body temperature.
Colour	Even through the length	Cut one lengthways. Streaking means the jug was not stirred.
Seal	Intact on every shell	Squeeze test on ten.

Any result outside target holds the batch.

2.7 Batch Record

Advanced Care
Batch number		BNH-ADV-____
Date and operator
Distillate lot
CBD, CBG, CBN isolate lots
CBDa, CBGa isolate lots
CBC liquid lot
Cocoa butter and apricot oil lots
Concentrate clear, no grit		yes or no
Concentrate reheated		yes or no
Cocoa butter melt time		minutes
Peak temperature, cocoa butter		°C, max 40
Both streams at Stage B		°C
First pour		°C
Last pour		°C, above 33
Reheat during pour		yes or no
Units filled		expect 300
Mean unit weight		g
Residue in beaker		g, under 45
Bloom check at 24 hours		pass or hold
Deviations
Released by and date